ADC-001
our first LBP in NASH/NAFLD
- Adlercreutzia equolifaciens is a commensal bacterium isolated in Japan in 2008
- Presence of Adlercreutzia is strongly correlated with the switch from NAFLD to NASH
- Associated with “healthy” status while it disappears in cirrhotics
- Reduces inflammation, decreases hyperglycemia and limits weight gain in in vivo models transplanted with NASH patient microbiota and force-fed with a high fat, high fructose diet
Coriobacteriaceae bacteria as our major focus
