NOVOBIOME FUTURE TECHNOLOGY PLATFORM
Aggregating four Methods of the Year from Nature Magazine
2007
Next Generation Sequencing
/ Metagenomics
Functional metagenomics
High-throughput screening platform MetaFUN from MGPS
High-throughput screening platform MetaFUN from MGPS
2008
Hi Resolution confocal
fluorescent microscopy
Hi Res confocal microscopy
Allows nanoscale resolution of cellular trafficking without diffraction limitation
Allows nanoscale resolution of cellular trafficking without diffraction limitation
2017
Organoids
Intestinal organoids
From human stem cells, differentiation makes it possible to obtain a pseudo intestine
From human stem cells, differentiation makes it possible to obtain a pseudo intestine
2018
Deep learning
for cell biology
Intestinal organoids
The platform will process 5,000 organoids/day X 10 images/second. An AI is needed to process the data & identify promising leads
The platform will process 5,000 organoids/day X 10 images/second. An AI is needed to process the data & identify promising leads
Disruptive ex-vivo discovery platform
- Metagenomics
- Transcriptomics
- Metabolomics
- Proteomics
Functional Metagenomics
functional analysis of the microbiota metagenome
Transcriptomics
gene expression in intestinal cells (inflammation, tight junctions, oxidative stress, etc.) and specific miRNAs
Metabolomics
identification of effector molecules
Proteomics / Lipidomics
characterization of proteins, SCFAs, primary & secondary metabolites & signaling pathways
