NOVOBIOME FUTURE TECHNOLOGY PLATFORM

Aggregating four Methods of the Year from Nature Magazine

2007

Next Generation Sequencing / Metagenomics
Functional metagenomics
High-throughput screening platform MetaFUN from MGPS

2008

Hi Resolution confocal fluorescent microscopy
Hi Res confocal microscopy
Allows nanoscale resolution of cellular trafficking without diffraction limitation

2017

Organoids
Intestinal organoids
From human stem cells, differentiation makes it possible to obtain a pseudo intestine

2018

Deep learning for cell biology
Intestinal organoids
The platform will process 5,000 organoids/day X 10 images/second. An AI is needed to process the data & identify promising leads

Disruptive ex-vivo discovery platform

  • Metagenomics
  • Transcriptomics
  • Metabolomics
  • Proteomics

Functional Metagenomics

functional analysis of the microbiota metagenome

Transcriptomics

gene expression in intestinal cells (inflammation, tight junctions, oxidative stress, etc.) and specific miRNAs 

Metabolomics

identification of effector molecules

Proteomics / Lipidomics

characterization of proteins, SCFAs, primary & secondary metabolites & signaling pathways